Decreased Calcium Tolerance in Nongoitrous Cretins

Electrocardiographic studies in cretins.

There is no direct method of estimating accurately the function of the thyroid gland; so other measures have to be employed in diagnosing thyroid deficiency and in regulating subsequent treatment. Recognition of typical cases of hypothyroidism should not be difficult, but there are borderline cases with slight symptoms that are not so easy to detect. Standard methods of investigation are helpfu...

Calcitonin secretion in congenital nongoitrous cretinism.

Plasma calcitonin (CT) was measured in the basal state and/or during provocative tests of hormone secretion in 11 children with congenital non-goitrous cretinism (CNC), in 1 girl with a lingual thyroid, and in 11 normal children. Basal and stimulated CT concentrations were significantly lower in the patients with CNC than in the normal subjects. Mean basal CT (+/- SE) was 41 +/- 4 pg/ml in the ...

Slow nerve conduction velocity in cretins.

Moosa, A., and Dubowitz, V. (1971). Archives of Disease in Childhood, 46, 852. Slow nerve conduction velocity in cretins. The ulnar and posterior tibial conduction velocities were measured in 6 untreated and 3 treated cretins. In 4 of the untreated patients, the conduction velocity of both nerves was slower than normal; in 1 patient the ulnar and in the other the posterior tibial nerve conducti...

Increased Red Cell Calcium , Decreased Calcium Adenosine

RBCs from four glucose-6-phosphate dehydrogenase (G6PD)-deficient (Mediterranean variant) subjects were studied during fava bean hemolysis. In the density-fractionated RBC calcium level, Ca2 -ATPase activity. reduced glutathione level. and ghost protein pattern were studied. In the bottom fraction, containing most heavily damaged RBCs, calcium level ranged from i43 to 244 smoI/L RBCs (healthy G...

Lunatics, Idiots, and Cretins in France